Synthesis of Pyrazolopyrazol Derivative via Reactions of Donor Compounds with 4-(2-Hydroxybenzylidene)-3-methyl-1H-pyrazol-5(4H)-one

Ashraf H.  Abou-Zied; Salema A. A.  El-Mansory

doi:10.54172/mjsc.v29i1.267

Authors

Ashraf H. Abou-Zied Chemistry Department, Faculty of science, Omar Al-Mukhtar University, Al-Beida, Libya
Salema A. A. El-Mansory Chemistry Department, Faculty of science, Omar Al-Mukhtar University, Al-Beida, Libya

DOI:

https://doi.org/10.54172/mjsc.v29i1.267

Keywords:

Pyrazole, acythiosemicarbazide, thiosemicarbazide, Pyrazolopyrazol

Abstract

4-(2-hydroxybenzylidene)-3-methyl-1H-pyrazol-5(4H)-one 3 reacted with hydrazine, phenylhydrazine, semicarbazide, thiosemicarbazide, acylthiosemicarbazide and acetylthiosemicarbazide as donor compounds in ethanol in presence of acetic acid or sulphuric acid by reflux to form pyrazolopyrazole derivative s 4 to 9, Respectively. These products which have been characterized by FT-IR, ¹H-NMR, ¹³C-NMR, mass spectra and elemental analysis have been produced in good yields.

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References

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