Gene flow of IA, IB and 1° alleles in Libya

Abstract

This study was carried out on a sample of 22752 individuals frawn from the Eastern part of Libya (Tubrak, Derna, Shahat, El-Beida, El-Merg, Benghazi). The objective was to evaluate the gene flow of IA, IB, and 1° alleles between Egypt and Libya, and to explore therelationship among the blood groups and diabetes, hypertension, asthma, and stomach ulcer. It was found that gene frequency has changed over the last 40 years since the last wave of migration started from Egypt to Libya. As a result of this migration gene frequency became 0.57, 0.25 and 0.15 for 1° 1A and IB respectively. The study indicates that there is a relationship between blood groups and diabetes millets and hypertension, whereas the asthma and stomach ulcer showed no relation with blood groups.