https://omu.edu.ly/journals/index.php/mjsc/issue/feedAl-Mukhtar Journal of Sciences2023-09-30T00:00:00+00:00Ali A. Batawomu.j.sci@omu.edu.lyOpen Journal Systems<div id="div-desktop"> <div class="row"> <div class="column1" style="background-color: #fff;"> <p><img src="https://omu.edu.ly/journals/public/site/images/ali_saad/--.jpg" alt="" width="1349" height="1908" /></p> </div> <div class="column2" style="background-color: #fff;"> <p><strong>Al-Mukhtar Journal of Sciences </strong>is a <strong>peer-reviewed, open-access journal published free of charge</strong> by <a href="http://omu.edu.ly/" target="_blank" rel="noopener"><strong>Omar Al-Mukhtar University</strong></a><strong>. </strong>The journal was founded in 1991 and has been publishing articles in English covering a wide range of pure and applied sciences. It accepts original research articles and interesting case studies from anywhere in the world. <strong>In the journal’s electronic version, accepted articles are published after acceptance. In its hardcopy version, it is published quarterly. </strong></p> <p>The journal operates a <strong>double-blind peer review process</strong>, and the articles are made permanently available free of charge. The journal is funded by the university and does not charge submission or publication fees.</p> <p><strong>Aims</strong><strong> and Scope</strong><strong>: Al-Mukhtar Journal of Sciences </strong>focuses on promoting research in all fields of pure and applied sciences of local, regional and international interest.</p> <p> </p> <p> </p> <p> </p> <h3> </h3> <p><span style="color: #000080;"> </span></p> </div> </div> </div> <div id="div-mobile"> <div style="background-color: #fff;"> <p><img class="mobile-image" src="https://omu.edu.ly/journals/public/site/images/ali_saad/---c06b17fda1aacfad6e83e24991446ba4.jpg" alt="" /></p> <p><strong>Al-Mukhtar Journal of Sciences </strong>is a peer-reviewed and open-access journal published by <strong><a href="http://omu.edu.ly/">Omar Al-Mukhtar University</a></strong><strong>. </strong>It was founded in 1991 and has been publishing original English articles quarterly, covering a wide range of pure and applied science providing global researchers with a free publishing platform. MJSc publishes its research through its electronic and paper versions printed upon request.</p> <p><strong>Aims and Scope: </strong>MJSc focuses on promoting sciences generated from<strong> Pure and Applied sciences</strong> to integrate research in all aspects. MJSc publishes <strong>Original Articles</strong> in addition to interesting <strong>Case Reports</strong>.</p> <p> </p> </div> <div style="background-color: #fff;"> <p> </p> </div> </div>https://omu.edu.ly/journals/index.php/mjsc/article/view/1137Breastfeeding Practices During Neonatal Period in Benghazi2022-12-19T17:07:34+00:00Arwa Gargoumesaida.elzaroug@uob.edu.lyIsaaida A. Elsaeitiesaida.elzaroug@uob.edu.lyNema Elhouniesaida.elzaroug@uob.edu.ly<p>Breastfeeding is the safest and healthiest infant feeding method; exclusive breastfeeding for the first 6 months of infant life is strongly advised. This study was conducted to assess infant feeding practice and maternal determinants of infant feeding during the first month of life. In a hospital-based cross-sectional survey at the neonatal unit and OPD of Benghazi Pediatric Hospital, mothers were selected by reason of infant age not exceeding 4 weeks. A sample of 306 mothers was collected, and the alarming results are that about 1/3(31.8%) of the mothers are either not breastfeeding their babies or practicing inappropriate early weaning (mixing). Moreover, inadequate milk production (25%) was reported as the most common cause of these practices. In addition, the role of the trustworthy education channel about breastfeeding is minimal, if not there, such as mother and child health care. Also, providers are the source of knowledge for only 2.38%. Operative delivery is associated with a marked delay in breastfeeding initiation (Pearson Chi-square =13.2, P=0.001), and older age group mothers are associated with a greater probability of operative delivery, hence it is an in-direct mediator of delayed breastfeeding initiation. These results reflect poor maternal knowledge and attitude about breastfeeding that ultimately resulted in poor practice and a low rate of exclusive breastfeeding, in addition to the limited awareness of healthcare providers about the importance of early initiation of breastfeeding to encourage the mothers and guide them to breastfeed their babies immediately after birth.</p>2023-09-30T00:00:00+00:00Copyright (c) 2023 Arwa Gargoum, Isaaida A. Elsaeiti, Nema Elhounihttps://omu.edu.ly/journals/index.php/mjsc/article/view/1253Rehabilitation Followings Surgical Fixation of Bimalleolar Fractures2023-02-03T06:26:04+00:00Mabrouk S. Bohalfayabohalfaya101065@gmail.comIdris M. Tajourybohalfaya101065@gmail.comHosam A. Ibraheembohalfaya101065@gmail.com<p>Fractures of the ankle are the commonest type of lower limb fractures and one of the most not unusual type of fractures all over the world. Purpose was to ascertain how powerful and safe are interventions that are used for rehabilitation following surgical treatment of bimalleolar fractures. This was a prospective study conducted on 60 individuals who were subjected to surgical fixation of bimalleolar fractures within the period of 2015 to 2017 at Aljalaa trauma hospital in Benghazi - Libya. The patients were randomly divided according to the sort of rehabilitation protocol into; Group A: who commenced early weight bearing (EWB) by below knee orthosis, and Group B: who began non-weight bearing (NWB) exercises by means of axillary crutches. Olerud Molander Ankle score (OMAS) was used to assess clinical results. Group A had higher OMAS rating than group B but out a significant statistical difference, and there was no significant difference regarding SF-36 scores. No significant difference between early weight bearing rehabilitation and non-weight bearing one as regard functional outcomes. Considering patient's comfort, early functional improvement, and the low complication rate, early postoperative weight bearing and range of motion (ROM) exercises are recommended in subjects with surgically treated ankle fractures.</p>2023-09-30T00:00:00+00:00Copyright (c) 2023 Mabrouk S. Bohalfaya, Idris M. Tajoury, Hosam A. Ibraheemhttps://omu.edu.ly/journals/index.php/mjsc/article/view/1295Complications of ventilation tube insertion in otitis media with effusion2023-02-20T19:22:05+00:00Halima A. Al Sheeyabhalimaalbargaty@gmail.comHussain A Belkhairkhamry1970@yahoo.comAgila A. AssanousiElmostashar1983@gmail.comMohammad A. shultamim.elshultame@gmail.com<p>Otitis media with effusion (OME) is the accumulation of fluid in the middle ear space without any symptoms of inflammation. It leads to decreased hearing and delayed speech in children. It is treated by ventilation tube insertion. These tubes may have complications itself like otorrhea, eardrum atrophy, perforation, serous otitis media, and tympanosclerosis. The aim of this study is to evaluate the complications of ventilation tube insertion in 100 cases done at specialty surgical center of otolaryngology/Benghazi over a period of one year (January 2021 to December 2021). Complications was seen in 42% of the cases, the most frequent complication was otorrhea followed by tympanosclerosis. the least encountered complication was tympanic membrane atrophy. Serious complications may be seen in some cases like cholesteatoma but it was not reported in this series. There was no statistically difference between male and female in terms of post-operative complications. It is advised to follow up these operated cases regularly to diagnose any complication and treat it early and properly.</p>2023-09-30T00:00:00+00:00Copyright (c) 2023 Halima A. Al Sheeyab, Hussain A Belkhair, Agila A. Assanousi, Mohammad A. shultamihttps://omu.edu.ly/journals/index.php/mjsc/article/view/1320Factors Influencing Postoperative Hospital Stay Following Colorectal Cancer Resection2023-03-17T19:48:54+00:00Naseralla J. Elsaadielsaadidawn@gmail.comSara I. El Fallahelsaadidawn@gmail.com<p>Colorectal cancer, a prevalent ailment with a growing prevalence due to aging populations, presents surgical, chemotherapy, and radiation therapy as its chief treatment modalities. Our study sought to pinpoint the determinants of hospitalization duration (LOS) in colorectal cancer patients, encompassing both planned and emergency admissions, acknowledging the considerable impact on healthcare costs nationally and internationally. conducting a retrospective data analysis encompassing patients subjected to colorectal cancer surgery at Benghazi Medical Centre (BMC) from January 2016 to December 2018, we meticulously compiled and assessed demographics, clinical symptoms, surgical particulars, postoperative complications, comorbidities, and LOS. Statistical significance was ascertained at a threshold of P < 0.05. amongst the cohort of ninety-eight colorectal cancer surgery recipients, the exclusion of four due to missing data resulted in a study cohort of ninety-four cases. The median LOS stood at 11.7 days, with five notable factors significantly extending LOS: enter cutaneous fistula, wound infection, diabetes mellitus (DM), emergency procedures, and postoperative complications. This investigation conducted at BMC ascertained that diabetes mellitus, emergency admissions, postoperative wound infections, and fistula development correlated with prolonged LOS. A discernible increase in hospital stays was evident in elderly patients afflicted with comorbidities and diabetes. These revelations bear substantial financial implications.</p>2023-09-30T00:00:00+00:00Copyright (c) 2023 Naseralla J. Elsaadi, Sara I. El Fallahhttps://omu.edu.ly/journals/index.php/mjsc/article/view/1340Abdominal Wall Endometriosis (AWE): A New Surgical Challenge (Case Report)2023-04-04T15:26:09+00:00Yousuf Ballaluyousufanoure@gmail.comHusayn AlfakhakhiriYousefanoure@gmail.comFathe shalwi Yousefanoure@gmail.comAsmahan Alshaykh Yousefanoure@gmail.comMustafa MusabihahYousefanoure@gmail.comAhmed Aloukiliahmadmmalawkaly@gmail.com<p>Endometriosis is defined as the appearance of functional uterine tissue that responds to hormonal stimuli in tissues other than the uterine cavity. Typically, the pelvic cavity is where endometriosis is found. The anterior abdominal wall, bone, adrenal glands, eyes, and heart are all occasionally involved in extrapelvic cases. The most typical symptom of extrapelvic endometriosis is abdominal wall involvement. There appears to be a strong correlation between pre-existing surgical scars and the presence of endometriomas within the abdominal wall. In cases when female patients exhibit a cyclically painful abdominal wall mass, it is crucial to maintain a heightened level of suspicion for endometrioma, particularly if there is a history of prior gynecologic surgery. The differential diagnosis may provide greater challenges when abdominal wall endometriomas are situated at a distance from the scar, as is commonly observed following Pfannenstiel's laparotomic incision. Many of these lesions can be distinguished by MRI, and intraoperative frozen section histological confirmation should be obtained to enable an oncological resection if necessary.</p>2023-09-30T00:00:00+00:00Copyright (c) 2023 Yousuf Ballalu, Husayn Alfakhakhiri, Fathe shalwi , Asmahan Alshaykh , Mustafa Musabihah, Ahmed Aloukilihttps://omu.edu.ly/journals/index.php/mjsc/article/view/1349Development and validation of HPLC-UV method for determination of Metformin Hydrochloride in Tablets available in the Libyan market2023-04-18T22:09:06+00:00Osama I. G. Khreitosama.khreit@omu.edu.lyMarwa M. Badermarwa.mousa@omu.edu.lyAmna M. Imbarakamnazaidan26@gmail.comKhoud M. Yacoubkhoudmmy2918@gmail.comKhawla A. JomaaKhawla98abdalrasool@gmail.comRowaida A. Aboubakrrowaida.almontaser@omu.edu.ly<p>A rapid and simple HPLC-UV method has been developed and validated for the estimation of metformin HCl formulated in tablet dosage form, as well as to identify different commercial brands of metformin HCl using BP test Thin Layer Chromatography. The HPLC method was performed on a Reversed-Phase Brownlee Bio C18 column (250 x 4.6 mm, 5 μm) at a 1.0 mL min<sup>-1</sup> flow rate with UV detection at 236 nm. The mobile phase was conducted in an isocratic manner and contained 52% acetonitrile and 48% aqueous phase (0.1M Potassium dihydrogen orthophosphate). The pH of the aqueous phase was adjusted to 5.5. The validation of the analytical method for determination of metformin HCl in tablet formulation was performed following parameters including system suitability, specificity, the limit of quantification, limit of detection, peak shapes, and asymmetries have resulted. The precision was calculated and showed excellent reproducibility (RSD = 0. 1-0.57 %, n=3). The linearity of the method has been tested in the range of 4.0–12.0 µg mL<sup>-1</sup> for metformin HCl. The limits of detection and quantification have been also established to be lower than 2.7 µg mL<sup>-1</sup> and 8.0 µg mL<sup>-1</sup>, respectively. This method is suitable to estimate pharmaceutical formulations with no interference from excipients.</p>2023-09-30T00:00:00+00:00Copyright (c) 2023 Osama I. G. Khreit, Marwa M. Bader, Amna M. Imbarak, Khoud M. Yaqoub, Khawla A. Jomaa, Rowaida A. Aboubakrhttps://omu.edu.ly/journals/index.php/mjsc/article/view/1375Expression and Significance of Vascular Endothelial Growth Factor Receptors 2 and 3 in Endometrial Carcinoma2023-05-22T20:17:18+00:00Nadia Y. Ibrahiemnada.elsafi1610@gmail.com<p>The aim of this work is to evaluate the expression and significance of Vascular Endothelial (VEGFR2,3) in endometrim. The study was applied to 70 females selected from El-Shatby University Hospital. Group I: 35 patients with dysfunctional uterine bleeding. Group II: 35 patients diagnosed with endometrial carcinoma. In the present work, VEGFRs 2 and 3 expression was detected by quantitative real-time PCR. The results revealed that: regarding relative VEGFR gene quantitation, there were no significant differences in the rates of VEGFR 2 and 3 expression between controls and cases. Regarding VEGFR 2 and 3 with type I & II, low and high histological grade, early and late stage, and lymphovascular invasion of endometrial cancer cases, there was no statistically significant relation. In this particular study, it was concluded that the expression levels of VEGFR2 and VEGFR3 do not exhibit any significant increase in endometrial cancers compared to dysfunctional uterine bleeding. Furthermore, we have observed that there exists no discernible correlation between VEGFR2 and VEGFR3 with regard to the histological type, grade, stage, or lymphovascular invasion of the endometrial cancer case.</p>2023-09-30T00:00:00+00:00Copyright (c) 2023 Nadia Y. Ibrahiemhttps://omu.edu.ly/journals/index.php/mjsc/article/view/1458The Relationship of Betatrophin and Kisspeptin with Related Hormones in Women Newly Diagnosed with Polycystic Ovary Syndrome2023-07-27T20:34:42+00:00NoorEmad Alattarnooremadyounisqas@gmail.comAbeer A. Al–HadidyAbesbio53@uomosul.edu.iq<p>Polycystic ovary syndrome (PCOS) is one of the most widespread endocrine hormone disorders that affects women of reproductive age. It’s a major public health concern that leads to dysregulations in the reproductive, metabolic, and psychological systems. Anovulation, which has a significant impact on female fertility, and hyperandrogenism are the most characteristic of PCOS. Because of its endocrine role, adipose tissue secretes several proteins called adipokines that work as hormones controlling bodily functions, including resistin, betatrophin, etc. The cases involved in this study were 90 women. For comparison, 30 healthy women with regular periods suitable with age were used as a control group. 30 Obese PCOS women were diagnosed depending on the Rotterdam criteria as group<sub>2</sub>, and 30 non-obese PCOS women as group<sub>3</sub>. The results showed there was a significant elevate in insulin and insulin resistance and related hormones between groups compared to the control, and a significant increase at (P≤ 0.01) in levels of betatrophin in group<sub>2</sub> compared to the control, with a significant difference between the group<sub>2 </sub>and group<sub>3,</sub> and a significant increase at (P≤ 0.01) in levels of kisspeptin in group<sub>2</sub> compared to the control. No significant difference between group<sub>2</sub> and group<sub>3</sub> and a significant difference between group<sub>3</sub> and the control group.</p>2023-09-30T00:00:00+00:00Copyright (c) 2023 NoorEmad Alattar, Abeer A. Al–Hadidyhttps://omu.edu.ly/journals/index.php/mjsc/article/view/1461Non- Compliance of Patients with Antibiotic Prescriptions 2023-07-31T18:21:33+00:00Taher I. Shailabitaher.issa@omu.edu.lyNisreen S. Majeednisreen.saad@omu.edu.lyElham O. BorwisDentelham@gmail.comNagat H. Bubtinanagat_bub@yahoo.com<p>Non-compliance with antibiotic treatment instructions is dangerous in complete cure, increasing treatment costs and increasing the number of resistant microbes. This study aimed to assess adherence to antibiotic treatment and its associated factors in patients after visiting Libyan community pharmacies. A cross-sectional study was conducted on patients who visited community pharmacies in Libya. Several reasons for non-compliance have been reported but the main ones were it is not necessary to continue taking prescribed medications once feeling better (27.3%), polypharmacy (19.6%), fear of medication adverse effects (18.7%) and the duration of antibiotic treatment also increased the risk of non-compliance (15%). Appropriate prescribing strategies to increase the public awareness, knowledge, and attitude to ensure appropriate antimicrobial use and minimize the problem of non-compliance.</p>2023-09-30T00:00:00+00:00Copyright (c) 2023 Taher I. Mahmod Shailabi, Nisreen S. Majeed, Elham O. Borwis, Nagat H. Bubtina