Investigation into Causes of Allergic Diseases Using Quantitative Measurement of Allergen-Specific Ige in Serum in Al- Bayda, Libya

Abdulsalam  Elfowiris; Monier  Sharif; Salma  Bianco

doi:10.54172/mjsc.v33i4.305

Authors

Abdulsalam Elfowiris Department of Pharmacology and Toxicology, Faculty of Pharmacy, Omar Al-Mukhtar University, Al-Bayda- Libya
Monier Sharif Department of Pathology and Anatomy, Faculty of Veterinary, Omar Al-Mukhtar University, Al-Bayda- Libya
Salma Bianco Ministry of health, Al-Bayda- Libya

DOI:

https://doi.org/10.54172/mjsc.v33i4.305

Keywords:

Immunoglobulin E (Ig E),, house dust mite (HDM), atopic dermatitis

Abstract

Allergy is a complex condition that results from different causative factors and different kinds of reactions, which caused by vibrant interactions ranged from genetic predisposition, environmental factors, food reaction, animals, insects, to a dysfunctional immune system. A public concern has grown in response to the increasing prevalence of allergy and related atopic conditions. Although the underlying mechanism of the true causes of allergy is complicated due to insufficient data and variable methodologies, Immunoglobulin E (Ig E) is commonly accepted as a specific index for allergic diseases among many indices used to test allergy. The aim of the study was to perform analysis of food allergens, inhalatory allergens, and other allergens types in patients diagnosed with an allergy by testing specific IgE to understand the risk factors, prediction, preventing, and determine the treatment. The results showed that specific IgE serum levels are significantly higher in patients sensitized to D. pteronyssinus and D. farinae allergens. However, more data and studies are needed to investigate the local allergens that cause allergy.

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