Non- Compliance of Patients with Antibiotic Prescriptions

Authors

  • Taher I. Shailabi Department of Pharmacology and Toxicology, Faculty of Pharmacy, Omar Al-Mukhtar University, Libya https://orcid.org/0000-0003-4504-1722
  • Nisreen S. Majeed Department of Pharmacology and Toxicology, Faculty Of Pharmacy, Omar Al-Mukhtar University, Libya
  • Elham O. Borwis Department of Medical Microbiology, Faculty Of Medicine, Benghazi University
  • Nagat H. Bubtina Department of Dentistry, Faculty of Dentistry, Benghazi University, Benghazi, Libya

DOI:

https://doi.org/10.54172/mjsc.1461

Keywords:

Antibiotics, Bacterial resistance, Community pharmacies, Patient adherence, Libya

Abstract

Non-compliance with antibiotic treatment instructions is dangerous in complete cure, increasing treatment costs and increasing the number of resistant microbes. This study aimed to assess adherence to antibiotic treatment and its associated factors in patients after visiting Libyan community pharmacies. A cross-sectional study was conducted on patients who visited community pharmacies in Libya. Several reasons for non-compliance have been reported but the main ones were it is not necessary to continue taking prescribed medications once feeling better (27.3%), polypharmacy (19.6%), fear of medication adverse effects (18.7%) and the duration of antibiotic treatment also increased the risk of non-compliance (15%). Appropriate prescribing strategies to increase the public awareness, knowledge, and attitude to ensure appropriate antimicrobial use and minimize the problem of non-compliance.

Downloads

Download data is not yet available.

References

Ahmed, N. J. (2020). The Rate of Adherence to Antibiotics and Reasons for Non-adherence among the Public. Journal of Pharmaceutical Research International, 32(7), 42–47.

Almomani, B. A., Hijazi, B. M., Awwad, O., & Khasawneh, R. A. (2022). Prevalence and predictors of non-adherence to short-term antibiotics: A population-based survey. PLoS ONE, 17(5 May), 1–11.

Atia, Ahmed. (2018). Monitoring the Level of antibiotic purchase without a prescription among Libyan young adults. Indian Journal of Pharmacy Practice, 11(4), 208–211.

Atia, Ahmed. (2020). Epidemiology of Self-Medication Practice among Libyans: A Systematic Review and Meta-Analysis. Preprints, June, 1–9.

Atia, Ahmed, Abired, A., Ammar, A., Elyounsi, N., & Ashour, A. (2018). Prevalence and types of bacterial infections of the upper respiratory tract at a tertiary care hospital in the City of Tripoli. Libyan International Medical University Journal, 3(2), 54.

Atia, Ahmed, Elyounsi, N., Abired, A., Wanis, A., & Ashour, A. (2020). Antibiotic resistance pattern of bacteria isolated from patients with upper respiratory tract infections; a four-year study in Tripoli city. Iberoamerican Journal of Medicine, 03(August), 155–160.

Atia, Ahmed, Zanned, S., & Bakait, N. (2020). Exploring the Ready Knowledge of Drug Prescribing among Junior Doctors in Libya. 2020–2023.

Atia, AhmedE, & Abired, A. (2017). Antibiotic prescribing for upper respiratory tract infections by Libyan community pharmacists and medical practitioners: An observational study. Libyan Journal of Medical Sciences, 1(2), 31.

Bruyndonckx, R., Adriaenssens, N., Versporten, A., Hens, N., Monnet, D. L., Molenberghs, G., Goossens, H., Weist, K., & Coenen, S. (2021). Consumption of antibiotics in the community, European Union/European Economic Area, 1997-2017: Data collection, management and analysis. Journal of Antimicrobial Chemotherapy, 76, II2–II6.

Duan, L., Liu, C., & Wang, D. (2021). The general population’s inappropriate behaviors and misunderstanding of antibiotic use in China: A systematic review and meta-analysis. Antibiotics, 10(5).

Elbabour, F., Benkhaial, A., & Elemam, R. Antibiotic Prescribing Practices in Libya: A cross-sectional Survey.

Elzahaf, R. A., Rabeea, A. A., Mohamed, F. A., Ramadan, S., Fadhlalla, A., Alkhawwajah, T. A., & Shaheen, M. K. (2021). Knowledge, Attitude and Practice Regarding to Antibiotics use among Libyan Community. Saudi J Med Pharm Sci, 4929, 599–608.

Falagas, M. E., Karagiannis, A. K. A., Nakouti, T., & Tansarli, G. S. (2015). Compliance with once-daily versus twice or thrice-daily administration of antibiotic regimens: A meta-analysis of randomized controlled trials. PLoS ONE, 10(1), 1–15.

Fernandes, M., Leite, A., Basto, M., Nobre, M. A., Vieira, N., Fernandes, R., Nogueira, P., & Jorge, P. (2014). Non-adherence to antibiotic therapy in patients visiting community pharmacies. International Journal of Clinical Pharmacy, 36(1), 86–91.

French, G. L. (2005). Clinical impact and relevance of antibiotic resistance. Advanced Drug Delivery Reviews, 57(10), 1514–1527.

Ghaieth, M. F., Elhag, S. R. M., Hussien, M. E., & Konozy, E. H. E. (2015). Antibiotics self-medication among medical and nonmedical students at two prominent Universities in Benghazi City, Libya. Journal of Pharmacy and Bioallied Sciences, 7(2), 109–115.

Jimmy, B., & Jose, J. (2011). Patient medication adherence: Measures in daily practice. Oman Medical Journal, 26(3), 155–159.

Kardas, P. (2002). Patient compliance with antibiotic treatment for respiratory tract infections. Journal of Antimicrobial Chemotherapy, 49(6), 897–903.

Llor, C., Hernández, S., Bayona, C., Moragas, A., Sierra, N., Hernández, M., & Miravitlles, M. (2013). A study of adherence to antibiotic treatment in ambulatory respiratory infections. International Journal of Infectious Diseases, 17(3), 168–172.

Mohammed, M. A., Alnour, T. M. S., Shakurfo, O. M., & Aburass, M. M. (2016). Prevalence and antimicrobial resistance pattern of bacterial strains isolated from patients with urinary tract infection in Messalata Central Hospital, Libya. Asian Pacific Journal of Tropical Medicine, 9(8), 771–776.

Organization, W. H. (2012). The evolving threat of antimicrobial resistance: Options for action. WHO Publications, 1–119. www.who.int/patientsafety/en/%0Ahttp://www.ijmr.org.in/article.asp?issn=0971-5916;year=2014;volume=139;issue=1;spage=182;epage=183;aulast=Kapi.

Pechère, J. C., Hughes, D., Kardas, P., & Cornaglia, G. (2007). Non-compliance with antibiotic therapy for acute community infections: a global survey. International Journal of Antimicrobial Agents, 29(3), 245–253.

Shailabi, T., Aldeeb, O. H., Almaedani, A. F., Borwis, E. O., & Amer, S. A. (2022). Antimicrobial Susceptibility Patterns of Escherichia coli from Urine Isolates. Al-Mukhtar Journal of Sciences, 37(4), 372–384.

Shailabi, T. I. M., & Akrim, Z. S. M. (2021). Disposal Methods of Expired and Unused Medications among the General Public in Al-Bayda City. Al-Mukhtar Journal of Sciences, 36(3), 209–215.

Thorpe, K. E., Joski, P., & Johnston, K. J. (2018). Antibiotic-resistant infection treatment costs have doubled since 2002, now exceeding $2 billion annually. Health Affairs, 37(4), 662–669.

Tong, S., Pan, J., Lu, S., & Tang, J. (2018). Patient compliance with antimicrobial drugs: A Chinese survey. American Journal of Infection Control, 46(4), e25–e29.

Downloads

Published

2023-09-30

How to Cite

Shailabi, T. I., Majeed, N. S., Borwis, E. O., & Bubtina, N. H. (2023). Non- Compliance of Patients with Antibiotic Prescriptions . Al-Mukhtar Journal of Sciences, 38(3), 315–322. https://doi.org/10.54172/mjsc.1461

Issue

Section

Research Articles

Categories