Effect of Marin Extract on Blood in Rats
DOI:
https://doi.org/10.54172/mjsc.v28i1.149Keywords:
Myrtus, Blood Picture, RatsAbstract
The aim of this study was to test the effect of the ethanolic extract of Myrtus leaves on the blood picture in White Rats. The animals were given a dose of 2 g/kg orally. A total of 28 rats were divided into 2 groups; 14 rats in each group. Each group included 7 animals as a control. The first group was given the dose daily for 7 days. The second group was treated for 14 days.
Some of the animals treated with the extract showed bleeding through mouth and nose. They were lethargic, tired and lost apetite. Furthermore, the weight of these animals was significantly lower than those in the controls.
With regard to blood picture , the treatment for one week caused significant reduction in the number of red blood corpuscles, packed cell volume, mean corpuscular volume, mean corpuscular haemoglobin concentration and number of platelets, while there were a significant increase in the white blood cells and lymphocytes. However, treating the animals with the extract for two weeks caused a significant reduction in the number of red blood corpuscles, packed cell volume , heamoglobin estimation and number of blood platelets, while there was an increase in mean corpuscular volume, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, white blood cells and the number of lymphocytes.
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