Prevalence of Metabolic Syndrome and Its Relation With Pro-Inflammatory Markers Among Group of Libyans

Authors

  • Salem M. Awami Faculty of medicine, Omar Al-Mukhtar University, Al-Bayda, Libya.
  • Faraj Alhomry Mohamed Faculty of medicine, Omar Al-Mukhtar University, Al-Bayda, Libya.

DOI:

https://doi.org/10.54172/mjsc.v33i2.178

Keywords:

Metabolic syndrome, International Diabetes Federation (IDF), body mass index (BMI), pro-inflammatory marker

Abstract

Metabolic syndrome (Met S) is known as the clustering of several metabolic abnormalities; it can be diagnosed according to several different criteria such as the International Diabetes Federation (IDF) criteria, which is intended for global application in clinical practice. Hematological tests (total Leukocyte count, differential count,  platelet count  and ESR) has been considered to be a marker of inflammation, several studies have examined the relationship between hematological tests, and components of metabolic syndrome; the data reveals correlations between it  and metabolic syndrome in some cross-sectional studies. The study used participants recruited from Albaida and Almarj cities outpatient clinic. History of hypertension, diabetes, Blood pressure, were taken, height, weight, and waist circumference were measured body mass index (BMI, kg/m²) was calculated. Blood samples were collected for hematological tests and others. The study subject was included and  categorized  according to IDF criteria. A total of 192 residents aged 16 to 85 years were investigated, 80 (41.7%) participants were Males and 112 (58.3 %) were Females. The mean BMI was 29 (St. Dev±07). Rates of underweight, normal weight, overweight and obesity were 4.7%, 24.5%, 27% and 43.75%, respectively.Prevalence of Metabolic Syndrome in our study according to IDF Criteria is 25.5 % ( males 12.5% and females 13%), central obesity, high plasma glucose, high blood pressure, elevated TG accounted for development of Met S.Inflammatory markers showed no significant difference between Met S and None-MetS groups, which could be explained by high prevalence of overweigh and obesity in none-MetSsyndrome persons in our study group

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References

Aguilar, M. Bhuket, T. Torres, S. Liu, B. and Wong, R. J. (2015). Prevalence of the metabolic syndrome in the United States, 2003-2012. The Journal of the American Medical Association 313 (19):1973-1974. DOI: https://doi.org/10.1001/jama.2015.4260

Aljohani, N. J. (2014). Metabolic syndrome: Risk factors among adults in Kingdom of Saudi Arabia. Journal of family & community medicine 21(3):170-175. DOI: https://doi.org/10.4103/2230-8229.142971

Boisvert, W. A. Santiago, R. Curtiss, L. K. and Terkeltaub, R. A. (1998). A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophages in atherosclerotic lesions of LDL receptor-deficient mice. Journal of Clinical investigation 101(2):353-363. DOI: https://doi.org/10.1172/JCI1195

Carnethon, M. R. Loria, C. M. Hill, J. O. Sidney, S. Savage, P. J. and Liu, K. (2004). Risk factors for the metabolic syndrome: the Coronary Artery Risk Development in Young Adults (CARDIA) study, 1985-2001.Diabetes care 27(11):2707-2715. DOI: https://doi.org/10.2337/diacare.27.11.2707

Dalvand, P S. Niksima, S. H. Meshkani, R. Gheshlagh, R.G. Sadegh-Nejadi, S. Kooti, W. Parizad N. Zahednezhad H. and Afrisham, R. (2017). Prevalen -ce of Metabolic Syndrome among Iranian Population: A Systematic Review and Meta-analysis. Iranian Journal Public Health; 46(4):456–467.

Danesh, J. Collins, R. Appleby, P. and Peto, R. (1998). Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: meta-analyses of prospective studies. The Journal of the American Medical Association 279(18):1477-1482. DOI: https://doi.org/10.1001/jama.279.18.1477

Genel, S. Floc,a E. Kudor-Szabadi, L. M. Lucia, S. Daniel, S. and Samasca, G. (2014). The relevance of inflammatory markers in metabolic syndrome. Maedica 9(1):15.

Grundy, S. M. (2008). Metabolic syndrome pandemic. Arteriosclerosis, thrombosis, and vascular biology 28 (4):629-636. DOI: https://doi.org/10.1161/ATVBAHA.107.151092

Grundy, S. M. Cleeman, J. I. Daniels, S. R. Donato, K. A. Eckel, R. H. Franklin, B. A. Gordon, D. J. Krauss, R. M. Savage, P. J. Smith, S. C. Spertus, J.A. and Costa, F. (2005). Diagnosis and management of the metabolic syndrome. Circulation 112(17):2735-2752. DOI: https://doi.org/10.1161/CIRCULATIONAHA.105.169404

IDF, (2006). The International Diabetes Federation consensus worldwide definition of the metabolic syndrome. P24

Imano, H. Sato, S. Kitamura, A. Kiyama, M. Ohira, T. Shimamoto, T. and Iso, H. (2007). Leukocyte count is an independent predictor for risk of acute myocardial infarction in middle-aged Japanese men. Atherosclerosis 195 (1):147-152. DOI: https://doi.org/10.1016/j.atherosclerosis.2006.09.002

Maklady, F. A. Kamal, H. M. El-Eraky, A. Z. and Hassouna, O. H. (2014). Prevalence of metabolic syndrome among adults in Suez Canal area. The Egyptian Heart Journal 66 (1-Supplement) P 35. DOI: https://doi.org/10.1016/j.ehj.2013.12.043

WHO (1995). Physical Status: The Use and Interpretations of Anthropometry. World Health Organization Technical Report Series 854 P426.

WHO (1999). Definition, diagnosis and classification of diabetes mellitus and its complications: report of a WHO consultation. Part 1, Diagnosis and classification of diabetes mellitus.P59.

WHO (2000). Obesity: preventing and managing the global epidemic. World World Health Organization Technical Report Series 894, P252.

Sur G. Floca, E. Kudor-Szabadi, L. Sur, M. Sur, D. and Samasca, G. (2014).The Relevance of Inflammatory Markers in Metabolic Syndrome. Medica, A journal Of Clinical Medicine. 9(1): 15-18.

Ross, R. (1999). Atherosclerosis—an inflammatory disease. New England Journal Of Medicine 340(2):115-126. DOI: https://doi.org/10.1056/NEJM199901143400207

Wilson, P. W. D’Agostino, R. B. Parise, H. Sullivan, L. and Meigs, J. B. (2005). Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus. Circulation 112 (20) :3066-3072. DOI: https://doi.org/10.1161/CIRCULATIONAHA.105.539528

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Published

2018-06-30

How to Cite

Awami, S. M. ., & Mohamed , F. A. . (2018). Prevalence of Metabolic Syndrome and Its Relation With Pro-Inflammatory Markers Among Group of Libyans. Al-Mukhtar Journal of Sciences, 33(2), 131–138. https://doi.org/10.54172/mjsc.v33i2.178

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