The Incidence of Isolated Ventricular Septal Defect in Libyan Newborns

Authors

  • Mohamed Thabet Ali Department of Pediatrics, Faculty of Medicine Omar Al-Mukhtar University, Al-Bayda – Libya
  • Faiza Mohamed Ali Department of Pediatrics, Faculty of Medicine Omar Al-Mukhtar University, Al-Bayda – Libya

DOI:

https://doi.org/10.54172/mjsc.v36i2.59

Keywords:

Echocardiography, Newborn, Ventricular Septal Defect, Incidence

Abstract

This study aimed to evaluate the incidence and spontaneous closure of ventricular septal defects in a randomly selected newborn population, using color Doppler echocardiographic screening. Color flow Doppler echocardiographic screening was performed in 635 neonates within the first week of life. Patients with a ventricular septal defect were also followed up for 6 months to detect spontaneous closure rate and its timing. The incidences of a ventricular septal defect in all neonates, preterm neonates, and term neonates were found as 48.8/1,000, 64/1,000, and 48.1/1,000 live births, respectively. Only three patients were symptomatic. 21 cases had a muscular ventricular septal defect and 10 cases had a perimembranous ventricular septal defect. Most of them had a small ventricular septal defect (≤3 mm). Spontaneous closure was observed in 64.5% of ventricular septal defects within 6 months Closure rate was found as 80% for preterm infants and 66.8% for term infants (p>0.05). The incidence of a ventricular septal defect was considerably high in neonates when routine color flow Doppler echocardiographic examination was performed. Despite the increased incidence of ventricular septal defect, spontaneous closure rate was remarkably high within the first 6 months of life. These defects may result from delayed physiologic development and have a good prognosis.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Clark, E. B. (2001). Etiology of congenital cardiovascular malformations: epidemiology and genetics. Moss and Adams’ Heart Disease in Infants and Adolescents, 1, 64-79.

Du, Z.-D., Roguin, N., Barak, M., Bihari, S. G., & Ben-Elisha, M. (1996). High prevalence of muscular ventricular septal defect in preterm neonates. The American journal of cardiology, 78(10), 1183-1185. DOI: https://doi.org/10.1016/S0002-9149(96)90080-6

Du, Z.-D., Roguin, N., & Wu, X.-J. (1998). Spontaneous closure of muscular ventricular septal defect identified by echocardiography in neonates. Cardiology in the young, 8(4), 500-505. DOI: https://doi.org/10.1017/S1047951100007174

Hiraishi, S., Agata, Y., Nowatari, M., Oguchi, K., Misawa, H., Hirota, H., Fujino, N., Horiguchi, Y., Yashiro, K., & Nakae, S. (1992). Incidence and natural course of trabecular ventricular septal defect: two-dimensional echocardiography and color Doppler flow imaging study. The Journal of pediatrics, 120(3), 409-415. DOI: https://doi.org/10.1016/S0022-3476(05)80906-0

Hoffman, J. I., & Kaplan, S. (2002). The incidence of congenital heart disease. Journal of the American College of Cardiology, 39(12), 1890-1900. DOI: https://doi.org/10.1016/S0735-1097(02)01886-7

Miyake, T., Shinohara, T., Nakamura, Y., Fukuda, T., Tasato, H., Toyohara, K., & Tanihira, Y. (2004). Spontaneous closure of ventricular septal defects followed up from< 3 months of age. Pediatrics international, 46(2), 135-140. DOI: https://doi.org/10.1046/j.1442-200x.2004.01858.x

Park, M. (2014). Park’s pediatric cardiology for practitioners, ser. Pediatrics. Philadelphia, PA: Elsevier Saunders.

Roguin, N., Du, Z.-D., Barak, M., Nasser, N., Hershkowitz, S., & Milgram, E. (1995). High prevalence of muscular ventricular septal defect in neonates. Journal of the American College of Cardiology, 26(6), 1545-1548. DOI: https://doi.org/10.1016/0735-1097(95)00358-4

Sands, A., Casey, F., Craig, B., Dornan, J., Rogers, J., & Mulholland, H. (1999). Incidence and risk factors for ventricular septal defect in “low risk” neonates. Archives of Disease in Childhood-Fetal and Neonatal Edition, 81(1), F61-F63. DOI: https://doi.org/10.1136/fn.81.1.F61

Snider, A., Serwer, G., & Ritter, S. (1997). Echocardiography in Pediatric Heart Disease, Mosby-Year Book. Inc., St. Louis, Missouri, 29.

Downloads

Published

2021-06-30

How to Cite

Ali, M. T. ., & Ali, F. M. . (2021). The Incidence of Isolated Ventricular Septal Defect in Libyan Newborns. Al-Mukhtar Journal of Sciences, 36(2), 148–152. https://doi.org/10.54172/mjsc.v36i2.59

Issue

Section

Research Articles

Categories

Most read articles by the same author(s)

Obs.: This plugin requires at least one statistics/report plugin to be enabled. If your statistics plugins provide more than one metric then please also select a main metric on the admin's site settings page and/or on the journal manager's settings pages.