دراسة تجريبية حول تأثير المبيد الحشري كلوربايروفوس على الجرذان البيضاء ثانياً - التغيرات النسيجية الكيماوية

Ibrahim  S. H.. El-durssi; Ifdial   I. O. El-Awami; Ghyath  mahmoud; Fahim A. Benkhaial

doi:10.54172/mjsc.v13i1.669

Authors

Ibrahim S. H.. El-durssi Zoology Department / College of science / Omar El-Mukhtar University
Ifdial I. O. El-Awami Faculty of Agriculture, Plant Protection Department, Omar Almukhtar University, El-Bieda-Libya
Ghyath mahmoud College of veterinary medicine/Omar El-Mukhtar University
Fahim A. Benkhaial Food technology department / college of agriculture / Omar El-Mukhtar University

DOI:

https://doi.org/10.54172/mjsc.v13i1.669

Abstract

This Study performed to investigate the effect of Chlorpyrifos (one of the most used insecticides)on certain organs in rats .

The experimental animals were 110 male rats and were divided into four groups: the first group was used to determine the median lethal dose (LD₅₀) which appeared to be equal to (81.2)mg/Kg B.W. While the second group of rats received an oral daily doses of 1/10 LD₅₀. The third and fourth groups of rats were administered single oral dose of 1/10 LD₅₀ and 1/30 LD₅₀ respectively.

Although histochemical investigation revealed that the epithelial cells of the intestine, liver biliary system and kidney’s tubules both in control and experimental rats contained a mixture of acid and neutral mucopolysaccharidse. This reaction matching the histochemistry of both the mast cells and goblet cells in control and experimental rats.

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